Scientific Papers

Minimizing Asynchronies in Mechanical Ventilation: Current and Future Trends

.pdf | 1.47M

Carles Subira` MD, Candelaria de Haro MD, Rudys Magrans PhD, and Rafael Ferna´ndez MD PhD, and Lluís Blanch MD PhD

Publiched in Respitaroty Care the official journal of American Association of Respiratory Therapists. (February 2018)

The work related with AEGLE project is mentioned on pages 10-11.

 

AEGLE’s Cloud Infrastructure for Resource Monitoring and Containerized Accelerated Analytics

Konstantina Koliogeorgi (Nat. Tech. Univ. of Athens); Dimosthenis Masouros (Nat. Tech. Univ. of Athens); Georgios Zervakis
(Nat. Tech. Univ. of Athens) 24 July 2017

Published in: VLSI (ISVLSI), 2017 IEEE Computer Society Annual Symposium

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A critique of the regulation of data science in healthcare research in the European Union

John M. M. Rumbold; Barbara K. Pierscionek 

Published in BMC Medical Ethics 

2017 April 18

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Dataflow Acceleration of scikit-learn Gaussian Process Regression

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Paper submitted at the Workshop on Parallel Programming and Run-Time Management Techniques for Many-core Architectures and Design Tools and Architectures for Multicore Embedded  

2017 January 25

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The Effect of the General Data Protection Regulation on Medical Research’

John Mark Michael Rumbold; Barbara Pierscionek

Published in Journal of Medical Internet Research 2017; 19(2):e47

2017 February 24

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Machine Learning and Data Mining Methods in Diabetes Research

Ioannis Kavakiotisa, Olga Tsavec, Athanasios Salifoglouc, Nicos Maglaveras, Ioannis Vlahavasa, Ioanna Chouvardab

Published in Computational and Structural Biotechnology Journal

2017 January 08

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EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia

Young E, Noerenberg D, Mansouri L, Ljungström V, Frick M, Sutton LA, Blakemore SJ, Galan-Sousa J, Plevova K, Baliakas P, Rossi D, Clifford R, Roos-Weil D, Navrkalova V, Dörken B, Schmitt CA, Smedby KE, Juliusson G, Giacopelli B, Blachly JS, Belessi C, Panagiotidis P, Chiorazzi N, Davi F, Langerak AW, Oscier D, Schuh A, Gaidano G, Ghia P, Xu W, Fan L, Bernard OA, Nguyen-Khac F, Rassenti L, Li J, Kipps TJ, Stamatopoulos K, Pospisilova S, Zenz T, Oakes CC, Strefford JC, Rosenquist R, Damm F.

Published in Journal Leukaemia. 2016 November 28

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Restrictions in the T-cell repertoire of chronic lymphocytic leukemia: high-throughput immunoprofiling supports selection by shared antigenic elements

A Vardi, E Vlachonikola, M Karypidou, E Stalika, V Bikos, K Gemenetzi, C Maramis, A Siorenta, A Anagnostopoulos, S Pospisilova, N Maglaveras, I Chouvarda, K Stamatopoulos and A Hadzidimitriou

Published in Leukemia. 2016 November 25

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Antigen receptor stereotypy in chronic lymphocytic leukemia

Stamatopoulos K, Agathangelidis A, Rosenquist R, Ghia P.

Published in Journal Leukaemia. 2016 November 4.

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Computation Offloading and Resource Allocation for Low Power IoT Edge Devices

Paper submitted at the IEEE World-Forum of Internet-of-Things (WF-IoT 2016) 

2016 December 01

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Clusters of ineffective efforts during mechanical ventilation: impact on outcome

Katerina Vaporidi, Dimitris Babalis, Achilleas Chytas, Emmanuel Lilitsis, Eumorfia Kondili, Vasilis Amargianitakis, Ioanna Chouvarda, Nicos Maglaveras, Dimitris Georgopoulos

Published in Intensive Care Medicine. 2016 October 24

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Ineffective Efforts in ICU Assisted Ventilation: Feature Extraction and Analysis Platform

A. Chytas, K. Vaporidi, D. Babalis, D. Georgopoulos, N. Maglaveras, and I. Chouvarda, “Ineffective Efforts in ICU Assisted Ventilation: Feature Extraction and Analysis Platform,” in Artificial Intelligence Applications and Innovations: 12th IFIP WG 12.5 International Conference and Workshops, AIAI 2016, Thessaloniki, Greece.

Published in Proceedings, L. Iliadis and I. Maglogiannis, Eds. Cham: Springer International Publishing, 2016, pp. 642–650.

2016 September 16-18

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Clinical Impact Of Recurrently Mutated Genes On Lymphoma Diagnostics: State-Of-The-Art And Beyond

Rosenquist R, Rosenwald A, Du MQ, Gaidano G, Groenen P, Wotherspoon A, Ghia P, Gaulard P, Campo E, Stamatopoulos K; European Research Initiative on CLL (ERIC) and the European Association for Haematopathology (EAHP).

Published in Jounral Haematologica. 2016 September

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NF-κB activation in chronic lymphocytic leukemia: A point of convergence of external triggers and intrinsic lesions

Mansouri L, Papakonstantinou N, Ntoufa S, Stamatopoulos K, Rosenquist R.

Published in Seminars in Cancer Biology. 2016 August

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Distributed QoS management for internet of things under resource constraints

Farzad Samie, Vasileios Tsoutsouras, Sotirios Xydis, Lars Bauer, Dimitrios Soudris, Jörg Henkel

Published in the proceedings of the Eleventh IEEE/ACM/IFIP International Conference on Hardware/Software Codesign and System Synthesis

2016 October 01-07

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Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference

Panagiotis Baliakas, Anna Puiggros, Aliki Xochelli, Lesley-Ann Sutton, Florence Nguyen-Khac, Anne Gardiner, Karla Plevova, Eva Minga, Anastasia Hadzidimitriou, Renata Walewska, Helen McCarthy, Margarita Ortega, Rosa Collado, Teresa González, Isabel Granada, Elisa Luño, Jana Kotašková, Theodoros Moysiadis, Zadie Davis, Niki Stavroyianni, Achilles Anagnostopoulos, Jonathan C. Strefford, Sarka Pospisilova, Frederic Davi, Anastasia Athanasiadou, Richard Rosenquist, David Oscier, Blanca Espinet, Kostas Stamatopoulos

Published in Haematologica. 2016 July

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ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres

Veronika Navrkalova; Emma Young; Panagiotis Baliakas; Lenka Radova; Lesley-Ann Sutton; Karla Plevova; Larry Mansouri; Viktor Ljungström; Stavroula Ntoufa; Zadie Davies; Gunnar Juliusson; Karin E. Smedby; Chrysoula Belessi; Panagiotis Panagiotidis; Tasoula Touloumenidou; Frederic Davi; Anton W. Langerak; Paolo Ghia; Jonathan C. Strefford; David Oscier; Jiri Mayer; Kostas Stamatopoulos; Sarka Pospisilova; Richard Rosenquist and Martin Trbusek.

Published at Haematologica journal

2016 June 08

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Why patients shouldn’t “own” their medical records

John Rumbold; Barbara Pierscionek

Published in Nature Biotechnology 2016; 34(6): 586

2016 June 09

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Performance-Power Exploration of Software-Defined Big Data Analytics: The AEGLE Cloud Backend

Paper submitted at the International Conference on Embedded Computer Systems: Architectures, Modeling, and Simulation (SAMOS 2016) 

2016 June 22

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Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: the case of “towards analysis” in chronic lymphocytic leukaemia

I. Kavakiotis, A. Xochelli, A. Agathangelidis, G. Tsoumakas, N. Maglaveras, K. Stamatopoulos, A. Hadzidimitriou, I. Vlahavas, and I. Chouvarda, “Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: The case of ‘towards analysis’ in chronic lymphocytic leukaemia,” BMC Bioinformatics, vol. 17, no. 5, 2016.

2016 June 6

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Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia with stereotyped B cell receptors

Lesley Ann Sutton (Uppsala University); Emma Young (Uppsala Universit); 
Panagiotis Baliakas Uppsala University); Anastasia Hadzidimitriou (Institute of Applied Biosciences, CERTH); 
Theodoros Moysiadis (Institute of Applied Biosciences, CERTH); Karla Plevova (Masaryk University and University Hospital Brno)Davide Rossi (Amedeo Avogadro University of Eastern Piedmont); Jana Kminkova Masaryk (University and University Hospital Brno); Evangelia Stalika (Institute of Applied Biosciences, CERTH); Lone Bredo Pedersen (Rigshospitalet); Jitka Malcikova (Masaryk University and University Hospital Brno); Andreas Agathangelidis (Universita' Vita-Salute San Raffaele); Zadie Davis (Royal Bournemouth Hospital); Larry Mansouri (Uppsala University); Lydia Scarfo' (Universita' Vita-Salute San Raffaele)Myriam Boudjoghra (Hopital Pitie-Salpetriere); Alba Navarro (University of Barcelona); Alice F. Muggen (University Medical Center Rotterdam); Xiao-Jie Yan (he Feinstein Institute for Medical Research); Florence Nguyen-Khac (Hopital Pitie-Salpetriere, Univ Paris 6); Marta Larrayoz (University of Southampton); Panagiotis Panagiotidis (University of Athens); Nicholas Chiorazzi (Institute for Medical Research); Carsten Utoft Niemann (Rigshospitalet); Chrysoula Belessi (General Hospital of Nikea); Elias Campo (Hospital Clinic de Barcelona); Jonathan C. Strefford (University of Southampton); Anton W. Langerak (University Medical Center Rotterdam); David Oscier (Royal Bournemouth Hospital); Gianluca Gaidano (Amedeo Avogadro University of Eastern Piedmont); Sarka Pospisilova (CEITEC MU and University Hospital Brno); Frederic Davi (Hopital Pitie-Salpetriere); Paolo Ghia (Universita' Vita-Salute, San Raffaele); Kostas Stamatopoulos (G. Papanicolaou Hospital) and Richard Rosenquist (Rudbeck Laboratory, Uppsala University).

Published at Haematologica journal

2016 May 12

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An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-2 04 Receptors

Vasilis Bikos, Maria Karypidou, Evangelia Stalika, Panagiotis Baliakas, Aliki Xochelli, Lesley-Ann Sutton, George Papadopoulos, Andreas Agathangelidis, Evdoxia Papadopoulou, Zadie Davis, Patricia Algara, George Kanellis, Alexandra Traverse-Glehen, Manuela Mollejo, Achilles Anagnostopoulos, Maurilio Ponzoni, David Gonzalez, Sarka Pospisilova, Estella Matutes, Miguel A Piris, Theodora Papadaki, Paolo Ghia, Richard Rosenquist, David Oscier, Nikos Darzentas, Dimitrios Tzovaras, Chrysoula Belessi, Anastasia Hadzidimitriou, and Kostas Stamatopoulos.

Published at Clinical Cancer Research – AACR journal. 2015 November 19

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Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?

Baliakas P, Mattsson M, Stamatopoulos K, Rosenquist R (Science for Life Laboratory, Uppsala; Uppsala University, Uppsala, Sweden; Center of Research and Technology Hellas Center of Research and Technology Hellas (CERTH), Thessaloniki, Greece). Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed? (Review). J Intern Med 2016; 279:347–357.

Published at Journal Internal Medicine. 2015 Dec 28 

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Novel Methods for Correcting Next Generation Sequencing Errors in the β Chain of T Cell Receptors

C. Panopoulou, C. Maramis, N. Maglaveras, and I. Chouvarda, “Novel Methods for Correcting Next Generation Sequencing Errors in the beta Chain of T Cell Receptors,” in XIV Mediterranean Conference on Medical and Biological Engineering and Computing 2016: MEDICON 2016, Paphos, Cyprus, E. Kyriacou, S. Christofides, and C. S. Pattichis, Eds. Cham: Springer International Publishing, 2016, pp. 529–534.

2016 March 31st-April 2nd 

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Design-Efficient Approximate Multiplication Circuits Through Partial Product Perforation

.pdf | 3.83M

Georgios Zervakis, Kostas Tsoumanis, Student Member, IEEE, Sotirios Xydis, Dimitrios Soudris, and Kiamal Pekmestzi

Published in: IEEE Transactions on Very Large Scale Integration (VLSI) Systems. 2016 March 15

Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?

Sarka Pospisilova, Lesley-Ann Sutton, Jitka Malcikova, Eugen Tausch, Davide Rossi, Emili Montserrat, Carol Moreno, Kostas Stamatopoulos, Gianluca Gaidano, Richard Rosenquist, Paolo Ghia

Published at the Haematologica journal. 2016 March

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A customizable framework for application implementation onto 3-D FPGAs

Kostas Siozios and Dimitrios Soudris. IEEE Transactions on Computer Aided Design. A customizable framework for application implementation onto 3-D FPGAs

Published at IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems. 2016 February 11

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Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

Viktor Ljungström, Diego Cortese, Emma Young, Tatjana Pandzic, Larry Mansouri, Karla Plevova, Stavroula Ntoufa, Panagiotis Baliakas, Ruth Clifford, Lesley-Ann Sutton, Stuart Blakemore, Niki Stavroyianni, Andreas Agathangelidis, Davide Rossi, Martin Höglund, Jana Kotaskova, Gunnar Juliusson, Chrysoula Belessi, Nicholas Chiorazzi, Panagiotis Panagiotidis, Anton W. Langerak, Karin E. Smedby, David Oscier, Gianluca Gaidano, Anna Schuh, Frederic Davi, Christiane Pott, Jonathan C. Strefford, Livio Trentin, Sarka Pospisilova, Paolo Ghia, Kostas Stamatopoulos, Tobias Sjöblom, and Richard Rosenquist

Published at Blood journal. 2016 February 25

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Reconfigurable Computing for Analytics Acceleration of Big Bio-Data: The AEGLE Approach

Andreas Raptopoulos, Sotirios Xydis, and Dimitrios Soudris, “Reconfigurable Computing for Analytics Acceleration of Big Bio-Data: The AEGLE Approach,” in Proceedings of ARC 2015, the 11th International Symposium on Applied Reconfigurable Computing, Bochum, Germany, pp. 531-5418.

2015 April 13-17

AEGLE: A Big Bio-Data Analytics Framework for Integrated Health-Care Services

.pdf | 1.62M

Dimitrios Soudris, Sotirios Xydis, Christos Baloukas, Anastasia Hadzidimitriou, Ioanna Chouvarda, Kostas Stamatopoulos, Nicos Maglaveras, John Chang, Andreas Raptopoulos, David Manset, Barbara Pierscionek, Reem Kayyali, Nada Phillip, Tobias Becker, Katerina Vaporidi, Eumorphia Kondili, Dimitrios Georgopoulos, Lesley-Ann Sutton, Richard Rosenquist, Lydia Scarfo, Paolo Ghia, “AEGLE: A Big Bio-Data Analytics Framework for Integrated Health-Care Services,” in Proceedings of International Conference on Embedded Computer Systems: Architectures, MOdeling and Simulation SAMOS XV Conference, Samos Island,

2015 July 20-23.

AEGLE: Accelerating Big Bio-Data Analytics with Reconfigurable HPC

Sotirios Xydis, Dimitrios Soudris, Tobias Becker and Georgi Gaydadjiev, “AEGLE: Accelerating Big Bio-Data Analytics with Reconfigurable HPC,” in ReC4P 2015 – First International Workshop on Reconfigurable Computing for HPC and HPDA, London, UK

2015 August 31

Effective Learning and Filtering of Faulty Heart-Beats for Advanced ECG Arrhythmia Detection using MIT-BIH Database

.pdf | 1.05M

Vasileios Tsoutsouras, Dimitra Azariadi, Sotirios Xydis, Dimitrios Soudris. "Effective Learning and Filtering of Faulty Heart-Beats for Advanced ECG Arrhythmia Detection using MIT-BIH Database". Institute of Communication and Computer Systems, Greece

Published in:
Proceeding MOBIHEALTH'15 Proceedings of the 5th EAI International Conference on Wireless Mobile Communication and Healthcare
Pages 50-53

2015 October 14-16

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Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia

Anna Vardi, Andreas Agathangelidis, Evangelia Stalika, Maria Karypidou, Alexandra Siorenta, Achilles Anagnostopoulos, Richard Rosenquist, Anastasia Hadzidimitriou, Paolo Ghia, Lesley-Ann Sutton, and Kostas Stamatopoulos

Published at Clinical Cancer Research – AACR journal. 2015 September 2

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A Systematic Methodology for Optimization of Applications Utilizing Concurrent Data Structures

Lazaros Papadopoulos, Ivan Walulya, Philippas Tsigas and Dimitrios Soudris, “Concurrent Data Structure Optimization Methodology for Embedded Systems,” accepted for publication in IEEE Transactions on Computers. DOI: 10.1109/TC.2015.2479604

2015 September 17

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Advancing Integrated and Personalized Healthcare Services, the AEGLE Approach

Andreas Raptopoulos, Vasileios Tsoutsouras and Dimitrios Soudris, “Advancing Integrated and Personalized Healthcare Services, the AEGLE Approach”, in CSE 2015 - Special Project Session on Cyber-Physical Systems, in the 18th IEEE International Conference on Computational Science and Engineering, Porto, Portugal,

2015 October 21-23.

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